The 2-Minute Rule for Promethazine codeine syrup
The 2-Minute Rule for Promethazine codeine syrup
Blog Article
Lengthy-expression animal scientific studies have not been done to evaluate the carcinogenic possible of codeine or of promethazine, nor are there other animal or human facts about carcinogenicity, mutagenicity, or impairment of fertility with these brokers.
In One more research one one hundred-mg/kg dose of codeine administered to pregnant mice reportedly resulted in delayed ossification in the offspring.
Epinephrine – Due to possible for promethazine to reverse epinephrine's vasopressor result, epinephrine shouldn't be employed to deal with hypotension connected with promethazine overdose.
The concomitant use of Promethazine HCl and Codeine Phosphate Oral Alternative with all cytochrome P450 3A4 inducers or discontinuation of the cytochrome P450 3A4 inhibitor may well bring about lessen codeine levels, bigger norcodeine amounts, and less metabolism by way of 2D6 with resultant decrease morphine concentrations.
A Specific MedGuide will likely be offered to you through the pharmacist with Every prescription and refill. You should definitely read this facts meticulously every time.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers less than 6 many years of age.
The causal role of opioids from the scientific syndrome of hypogonadism is mysterious since the numerous healthcare, physical, Life style, and psychological stressors that may affect gonadal hormone stages have not been adequately controlled for in studies conducted to this point [see Adverse Reactions (six)].
Patients must be recommended to measure promethazine with codeine syrup having an precise measuring device. A residence teaspoon isn't an accurate measuring gadget and could lead on to overdosage, particularly when a 50 percent a teaspoon is measured.
Selected from info integrated with permission and copyrighted by Initial Databank, Inc. This copyrighted materials has actually been downloaded from the licensed knowledge company and is not for distribution, other than as might be approved because of the applicable conditions of use.
Do not stand up or sit up promptly, particularly when you might be an older individual. This lowers the potential risk of dizzy or fainting spells. Alcoholic beverages could interfere Along with the outcome of the medication. Avoid alcoholic drinks.
Take this medication just as prescribed to lower the potential risk of habit. Request your medical doctor or pharmacist for more details.
Procedure of Overdose Remedy of overdosage is driven by the general scientific presentation, and contains discontinuation of Promethazine HCl and Codeine Phosphate Oral Answer together with institution of proper therapy. Give Most important attention for the reestablishment of ample respiratory exchange through provision of a patent and guarded airway plus the establishment of assisted or managed ventilation.
Be sure you know how to take this solution and what other medicines you should steer clear of getting with it. See also Drug Interactions section. Get clinical aid right away if any of those pretty major Uncomfortable side effects take place: slow/shallow respiratory, unusual lightheadedness, critical drowsiness/dizziness, difficulty waking up.
The outcome of promethazine and/or codeine over the Promethazine codeine syrup later progress and improvement from the new child is unfamiliar.